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Brain Matters: May 3, 2019

Physiology Based Management of TBI: Challenges to Guide Therapy


Clinical management of severe traumatic brain injury has traditionally been focused on control of intracranial pressure, which may be an insensitive and late indicator of secondary brain injury. The monitoring and treating of other physiologic variables, particularly brain tissue oxygenation (PbtO2), may enhance patient care. Insights regarding physiological changes in the brain may be determined through responses of PbtO2 to controlled changes in FiO2, CO2 and MAP. The methods to perform and interpret these dynamic "challenges" are the focus of this webinar.


  • Monitoring brain physiology
  • Performing FiO2, CO2, and MAP challenges
  • Interpreting results of challenges

Date Recorded:

Friday, May 3, 2019


The views and opinions expressed by the presenter and other third parties do not necessarily reflect those of Moberg Research, Inc. Moberg Research, Inc. makes no clinical claims regarding information described by the presenter and other third parties.